medical use of titanium dioxide supplier

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One of the most significant uses of titanium dioxide is in the production of paints and coatings. It acts as a pigment that provides brightness, opacity, and durability to the final product. The high refractive index of titanium dioxide allows it to scatter light effectively, making it ideal for creating opaque finishes. Moreover, its chemical stability ensures that the color remains consistent over time, even when exposed to harsh environmental conditions.

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Australian researchers examined how titanium dioxide as a food additive affected gut microbiota in mice by orally administering it in drinking water. The study, published in the journal Frontiers in Nutrition in 2019, found the treatment could “alter the release of bacterial metabolites in vivo and affect the spatial distribution of commensal bacteria in vitro by promoting biofilm formation. We also found reduced expression of the colonic mucin 2 gene, a key component of the intestinal mucus layer, and increased expression of the beta defensin gene, indicating that titanium dioxide significantly impacts gut homeostasis.” The changes were then linked to colonic inflammation, along with a higher expression of inflammatory cytokines, which are signal proteins that help with regulation. The researchers concluded that titanium dioxide “impairs gut homeostasis which may in turn prime the host for disease development.”

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